Encapon 200

Encapon 200

entacapone

Manufacturer:

Unison

Distributor:

Medline

Marketer:

Medline
Concise Prescribing Info
Contents
Entacapone
Indications/Uses
Adjunct to levodopa/benserazide or levodopa/carbidopa in patients w/ Parkinson's disease.
Dosage/Direction for Use
Adult 200 mg tab taken w/ each levodopa/dopa-decarboxylase inhibitor dose. Max: 200 mg 10 times daily.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Pheochromocytoma. History of NMS &/or non-traumatic rhabdomyolysis. Concomitant use w/ non-selective MAOI, selective monoamine oxidase (MAO)-A inhibitors + MAO-B inhibitors. Hepatic impairment.
Special Precautions
Orthostatic HTN/syncope, diarrhea/colitis, rhabdomyolysis, falling asleep during activities of daily living w/ or w/o somnolence, NMS, dyskinesia, compulsive behaviors/impaired impulse control. Patients w/ ischemic heart disease. Not recommended in childn <18 yr.
Adverse Reactions
Nausea, vomiting, urine discoloration, fatigue, increased sweating, fall, diarrhea, abdominal pain, dry mouth, constipation, dyskinesia, insomnia, hallucinations, confusion, nightmares, ischemic heart disease events.
Drug Interactions
Increased risk for bleeding w/ warfarin. Concomitant use w/ medicinal products metabolized by catechol-O-methyl-transferase (COMT) (eg, rimiterol, isoprenaline, adrenaline, noradrenaline, dopamine, dobutamine, α-methyldopa, apomorphine & paroxetine); chelates w/ Fe; drugs bound w/ human albumin binding site II (eg, diazepam & ibuprofen).
MIMS Class
Antiparkinsonian Drugs
ATC Classification
N04BX02 - entacapone ; Belongs to the class of other dopaminergic agents used in the management of Parkinson's disease.
Presentation/Packing
Form
Encapon 200 tab 200 mg
Packing/Price
1 × 10's;10 × 10's;3 × 10's
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